One-pot syntheses of novel pyrazole-containing bisphosphonate esters at room temperature.
نویسندگان
چکیده
An efficient general synthetic approach has been developed to synthesize pyrazole-containing bisphosphonate (N-BPs) esters from chromenone derivatives via a sequential two-step reaction in one pot at ambient temperature in good to excellent yields. This protocol provides a new convenient method to prepare lipophilic bisphosphonate precursors with potential activities.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 10 38 شماره
صفحات -
تاریخ انتشار 2012